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Frankfurt (officially: Frankfurt am Main (German: [ˈfʁaŋkfʊʁt ʔam ˈmaɪn]; Hessian: Frangford am Maa; lit"Frank ford on the Main")) is a metropolis and the largest city of the German federal state of Hesse, and its 746,878 (2017) inhabitants make it the fifth-largest city in GermanyOn the River Main (a tributary of the Rhine), it forms a continuous conurbation with the neighbouring city of Offenbach am Main, and its urban area has a population of 2.3 millionThe city is at the centre of the larger Rhine-Main Metropolitan Region, which has a population of 5.5 million and is Germany's second-largest metropolitan region after the Rhine-Ruhr RegionSince the enlargement of the European Union in 2013, the geographic centre of the EU is about 40 km (25 mi) to the east of Frankfurt's central business district.

Like France and Franconia, the city is named after the FranksFrankfurt is the largest city in the Rhine Franconian dialect area (Franconian dialects), Frankfurt was one of the host cities of the official tournaments of the 1974 and the 2006 FIFA World Cup. Frankfurt was a city state, the Free City of Frankfurt, for nearly five centuries, and was one of the most important cities of the Holy Roman Empire, as a site of imperial coronations; it lost its sovereignty upon the collapse of the empire in 1806 and then permanently in 1866, when it was annexed by the Kingdom of PrussiaIt has been part of the federal state of Hesse since 1945Frankfurt is culturally, ethnically, and religiously diverse, with half of its population, and a majority of young people, having a migration backgroundA quarter of the population consists of foreign nationals, including many expatriates. Frankfurt is an alpha world city and a global hub for commerce, culture, education, tourism and transportation.

It is the site of many global and European corporate headquartersFrankfurt Airport is among the world's busiestFrankfurt is the major financial centre of the European continent, with the headquarters of the European Central Bank, Deutsche Bundesbank, Frankfurt Stock Exchange, Deutsche Bank, DZ Bank, KfW, Commerzbank, several cloud and fintech startups and other institutesAutomotive, technology and research, services, consulting, media and creative industries complement the economic baseFrankfurt's DE-CIX is the world's largest internet exchange point.

Messe Frankfurt is one of the world's largest trade fairsMajor fairs include the Frankfurt Motor Show, the world's largest motor show, the Music Fair, and the Frankfurt Book Fair, the world's largest book fair. Frankfurt is home to influential educational institutions, including the Goethe University, the UAS, the FUMPA, and graduate schools like the Frankfurt School of Finance & ManagementIts renowned cultural venues include the concert hall Alte Oper, Europe's largest English theatre and many museums (e.gthe Museumsufer ensemble with Städel and Liebieghaus, Senckenberg Natural Museum, Goethe House, and the Schirn art venue at the old town)Frankfurt's skyline is shaped by some of Europe's tallest skyscrapers.